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Methadone
Synthetic narcotic , any of a number of substances that have a
depressant effect on the nervous system. The chief narcotic drugs are
opium , its constituents morphine and codeine , and the morphine
derivative heroin.
Actions and Uses
Similar in effect to morphine, principal derivative of opium , which is
the juice in the unripe seed pods of the opium poppy , Papaver
somniferum. Given intravenously, it is still considered the most
effective drug for the relief of pain.
It is sometimes used as an analgesic and to suppress the cough reflex.
In the brains of addicts, methadone prevents heroin, opiate drug
synthesized from morphine . Originally produced in 1874, it was thought
to be not only nonaddictive but useful as a cure for respiratory
illness and morphine addiction, and capable of relieving morphine
withdrawal symptoms.
Morphine from interacting with receptors for natural painkillers called
endorphins endorphins neurotransmitters found in the brain that
have pain-relieving properties similar to morphine. There are three
major types of endorphins: beta endorpins, found primarily in the
pituitary gland; and enkephalins and dynorphin, both distributed
throughout the nervous system.
Blocking the effects of the addictive drugs and reducing the physical
cravings. In controlled doses it creates its own effects of mild
euphoria and drowsiness, but lasts much longer (one to two days) and
does not create the sometimes fatal respiratory depression that opiates
do. Its continued use as a heroin substitute eventually restores
sexual, immune, and adrenal function. When methadone is given to a
heroin addict who is later withdrawn from methadone, the addict will
undergo methadone withdrawal instead of the more severe heroin
withdrawal.
Heroin opiate drug opiate drug, any of a group of drugs derived from
opium . Used medicinally to relieve pain and induce sleep, they include
codeine , morphine , the morphine derivative heroin , and, formerly,
laudanum . Sometimes included in the group are certain synthetic drugs
that have morphine like pharmacological action.
Synthesized from morphine morphine, principal derivative of opium ,
which is the juice in the unripe seed pods of the opium poppy , Papaver
somniferum. It was first isolated from opium in 1803 by the German
pharmacist F. W. A. Sertürner, who named it after Morpheus , the
god of dreams. Given intravenously, it is still considered the most
effective drug for the relief of pain.
Narcotic, any of a number of substances that have a depressant effect
on the nervous system. The chief narcotic drugs are opium , its
constituents morphine and codeine , and the morphine derivative heroin.
Effects and Addiction
Heroin is a central nervous system depressant that relieves pain and
induces sleep. It produces a dreamlike state of warmth and well-being.
It may also cause constricted pupils, nausea, and respiratory
depression, which in its extremes can result in death. Heroin activates
brain regions that produce euphoric sensations and brain regions that
produce physical dependence—hence its notorious ability to produce both
psychological and physical addiction.
Most heroin originates from opium poppy farms in SE Asia , SW Asia ,
and Latin American . The opium gum is converted to morphine in labs
near the fields and then to heroin in labs within or near the producing
country. After importation, drug dealers cut, or dilute, the heroin (1
part heroin to 9 to 99 parts dilutor) with sugars, starch, or powdered
milk before selling it to addicts; quinine white crystalline
alkaloid with a bitter taste.
Also added to imitate the bitter taste of heroin so the addict cannot
tell how much heroin is actually present. It is sold in single-dose
bags of 0.1 gram (0.03 oz.), each costing between $10 and $50 . One
pound of diluted heroin yields approximately 4,000 doses.
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